Saphyr, Bionano Genomics, Canada

Rapid optical genome mapping using whole genome imaging for human research applications

Saphyr features enhanced optics with adaptive loading of DNA utilizing machine learning. The Saphyr Instrument and high-capacity Saphyr Chip^® combine to deliver genome maps at the speed and scale your research demands.

• Long molecules from 150,000 bp to multi-megabase pairs
• 15 Tbp output per Saphyr Chip for human samples for deep structural variant discovery (5 Tbp per flowcell of molecules larger than 150 kbp)
• Sample to structural variation call or genome scaffolding in as little as 4 days

Optical genome mapping automation features and intelligent sample preparation simplify the process

Saphyr runs each genome in its own flow cell. Each Saphyr chip holds three flow cells, and 100x coverage of 3 human genomes is collected in less than 6 hours. That means 12 human samples at 100x coverage per day, or up to 96 per week.

For cases requiring higher coverage, like mosaic samples or heterogeneous tumors, the run can be extended up to 24 hours to collect as much as 400x coverage of a human genome for each of the three flowcells.